为了去除磷脂酰肌醇-3,4,5-三磷酸,第13外显子编码的arginine的3个密码子被设计成编码leucine。在通过cre介导的重组去除选择性用的loxP载体后,第14外显子下游保留了一个loxP位点。(来源:J:90081)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
其他
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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