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中文
转基因小鼠通过钙/钙调素依赖性蛋白激酶IIα(Camk2a)的驱动，在鼠模型中表达人类胰岛素降解酶(IDE)。定量Western blot分析和蛋白酶活性测定显示，相对于野生型对照，转基因表达大约是野生型的2倍。这些转基因小鼠在2至3个月时，可溶性αβ淀粉样蛋白X-40和可溶性αβ淀粉样蛋白X-42的水平有所降低。(来源：J:87150)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
