一个人类的OTX1 cDNA,连接了Otx2的5'和3' UTR,替换掉了所有的编码序列和内含子。这个等位基因仅保留了50bp的polyadenylation信号。它在Otx2的转录调控下表达人类的OTX1蛋白。(来源:J:89361)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
10
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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