将Cre重组酶连接到了Col1a1基因启动子的2.3kb区域。Col1a1的内源性启动子在成骨细胞分化过程中始终活跃,因此检测到Cre重组酶的表达仅限于骨骼中。细胞遗传学定位显示,转基因整合到了14qE2-4染色体上。(来源:J:77071, J:165282)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
插入
--
--
--
146

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部