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中文
大部分exon 3被替换成tau-lacZ报告基因和一个floxed PGK-neo插件。在启动子ATG位置引入了一个点突变，生成了终止密码子。X-gal染色显示突变大脑中有β-半乳糖苷酶活性。通过Northern blot检测，内源性mRNA缺失，而两步免疫测定证实了突变血浆中未检测到肽。(来源：J:89244)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
