在Mapk7tm1Jdl中,通过Cre介导的重组,4-7号外显子被剔除了,留下一个loxP位点。这些外显子编码了激酶区域和蛋白质的特有C端非激酶部分。用同源突变肝脏的 Western blot 实验确认了没有蛋白质表达。(来源:J:89215)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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