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中文
为了产生一个β亚型表达完全被抑制而α亚型表达保持不变的等位基因，科学家们插入了编码α亚型C端部分的cDNA以及一个polyA-neo插入片段到第20号外显子中。对纯合突变肝的RT-PCR和 Western blot分析证实了β亚型的缺失。α亚型转录物和蛋白的水平与野生型小鼠中检测到的水平相同。(来源：J:89194)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
