整个编码区域被替换为lacZ基因和伴随的核定位序列,接着是内含子和无启动子的诺卡因基因。Northern blot结果显示无转录本,而Western blot验证了没有蛋白质产物。β-半乳糖苷酶在淋巴结髓质中检测到表达,以及胸腺和脾脏少数细胞中也有所见。(来源:J:88538)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
插入,基因内删除
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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