Log In|Sign Up
中文
在exon 7的C到A替换突变导致了一个终止密码子，将酪氨酸替换为终止于第273位的氨基酸，这产生了非同义突变。实时PCR和免疫印迹结果显示，肝脏中Gck mRNA、蛋白表达和活性均下降。(来源：J:88919, J:137483)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
