通过同源重组,将编码RUNX1完整蛋白的cDNA插入了内源性位点的第4外显子。脾和胸腺中半定量RT-PCR分析显示,纯合突变鼠中突变转录本的水平与野生型鼠中正常转录本相当。(来源:J:87697)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
其他
--
1
8
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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