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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Prkaa1
tm1Sbj
Alias:
Ampk
-
alpha1AMPK
-
AMPKalpha1
-
Prkaa1
tm1Vio
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基础信息
表型特征
文献报道
将编码97到157这个催化区域的氨基酸序列替换成通过同源重组插入的IRES-betageo cassette。用来自纯合突变小鼠的肝脏和骨骼肌提取物进行 Western blot 分析,未检测到蛋白质。(来源:J:87719)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3029359
129S2/SvPas
Targeted
插入,基因内删除
--
1
--
113
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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