整个无内含子的编码区域被一个包含tau-lacZ和neo的盒式元件替换。通过 Western blot 分析,没有在纯合突变小鼠的视网膜中检测到蛋白质。(来源:J:87582)
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The entire, intronless, coding region was replaced with a cassette containing tau-lacZ and neo. Protein was undetected in the retinas of homozygous mutant mice by Western blot analysis. (J:87582)