从编码区域的760bp被替换成lacZ和抗氨苄青霉素耐药基因。替换序列包含了起始密码子以及编码前5个跨膜段的序列。RT-PCR结果显示,正常转录水平的不到10%,这可能是新抗氨苄青霉素基因的阅读通路效应,而非野生型转录本的结果。(来源:J:87803)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1+
Targeted
插入,基因内删除
--
1
--
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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