从编码区域的760bp被替换成lacZ和抗氨苄青霉素耐药基因。替换序列包含了起始密码子以及编码前5个跨膜段的序列。RT-PCR结果显示,正常转录水平的不到10%,这可能是新抗氨苄青霉素基因的阅读通路效应,而非野生型转录本的结果。(来源:J:87803)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count