在exon 1的上游插入了一个loxP位点,然后在 intron 1内插入了一个可剔除的诺卡因抗性基因座,这个基因座是floxed的。通过体外转染了pCre-Pac这种表达载体,一个经过定向克隆的ES细胞被处理,去除了floxed的诺卡因基因,保留了loxP标记的exon 1区域。(来源:J:91390)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部