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中文
Exon 3被替换了，通过同源重组插入了诺他霉素/卡那霉素抗性 cassette。缺失区域编码了126到251的氨基酸，这部分构成了辅酶A和钴胺素结合区域。在纯合突变小鼠的肝RNA中，通过RT-PCR分析未检测到转录本。来自突变小鼠的初级成纤维细胞中[14C]丙酸的同化显示，酶活性降低到野生型水平的大约6%。(来源：J:87081)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
