内源性位点在exon 3中通过插入编码EGFP的序列而发生了中断。在突变小鼠的海马组织提取物中,通过Western blot分析鉴定出了一种推测失去所有细胞内结合位点的截短蛋白,其胞质区域被GFP取代(来源:J:87398)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
1
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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