大部分第一个外显子被替换成一个带有IRES-lacZ表达座和PGK-诺卡因抗性基因的序列。 Western blot结果显示没有检测到蛋白产品。(来源:J:86936)
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Most of the first exon was replaced with an IRES-lacZ expression cassette and a PGK-neomycin resistance gene. Western blot analysis demonstrated the absence of protein product. (J:86936)