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中文
在第10个内含子中插入了floxed的耐药性基因，然后在第12个内含子中加入了一个loxP位点。通过表达Cre重组酶的正确靶向ES细胞的临时转染，去除了neomycin基因以及11和12号外显子。通过 Western blot 分析，证明了这些纯合小鼠中没有蛋白质产物产生。(来源：J:86770)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
