Icam2^tm1Jcgr

Exon 2 was disrupted by the insertion of a neomycin selection cassette. Protein was undetected by immunohistochemical analysis of homozygous mutant lung, kidney, liver, and spleen tissues. The absence of protein was further confirmed by flow cytometry, which showed no protein expression on the surface of homozygous mutant thymocytes, T or B lymphocytes, or myeloid cells. (J:54748)