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在第一段编码外显子的0.3千碱基被同源重组插入了诺卡因选择标记。通过RT-PCR分析，检测到了含诺卡因 cassette 的转录本，来自突变小鼠。检测到的转录本编码的突变蛋白缺乏催化单位，推测功能无效。在这些突变小鼠中，肌醇1,4,5-三磷酸3-激酶的活性以剂量依赖性减弱。(来源：J:86257)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
