Exon 1和上游序列被插入了通过同源重组插入的诺卡因选择标记。Exon 1编码起始密码子、推测的TMD1区域以及TMD1和TMD2区域之间的外显子连接区。在纯合突变小鼠的总肾RNA中,通过Northern blot分析未检测到转录本。(来源:J:86270)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count