Exon 1和上游序列被插入了通过同源重组插入的诺卡因选择标记。Exon 1编码起始密码子、推测的TMD1区域以及TMD1和TMD2区域之间的外显子连接区。在纯合突变小鼠的总肾RNA中,通过Northern blot分析未检测到转录本。(来源:J:86270)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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