一种新霉素筛选 cassette 替换了包含第3至5号外显子的基因组片段,这包括前3个编码外显子以及序列,大约2kb在第3号外显子上游。通过杂合突变小鼠的 RT-PCR 和 Western blot 检测,未发现突变转录本或蛋白质。(来源:J:86265)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入,基因内删除
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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