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中文
将人类的IL2RA基因插入了内源性位点的第二个外显子。靶向构建包含了IL2RA后面的poly(A)信号和一个新基因（neo）。通过将IL2RA单克隆抗体抗IL2RA的可变区连接到细菌外毒素，对突变小鼠进行重组免疫毒素处理，能够特异性地通过Drd2启动子消除表达IL2RA的细胞（来源：J:85929）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
