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中文
通过在原位引入工程性点突变，去除了Acetyltransferase(AT)活性。这些突变以天冬氨酸和丝氨酸替换色氨酸和酪氨酸(位置1503-1504的WY替换为WY(1503-1504)AS)。去除了用于选择的含loxP位点后，内含子前仍保留了一个单个的loxP座。 Western blot结果显示，突变蛋白的表达量与野生型相当。(来源：J:85950)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
