在经过同源重组引入的floxed neo cassette通过体外Cre介导的重组被剔除后,5、6和7号外显子的位置保留了一个loxP位点。在用针对N端特异性的抗体进行的 Western blot 检测中,野生型MEFs中未检测到蛋白质。(来源:J:85542)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入,基因内删除
--
1
--
30

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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