在第3外显子上游和第6外显子下游插入了LoxP位点,同时在第6内含子中插入了由FRT引导的PGK-neo载体。诺姆西林的插入导致基因表达降低,根据 Western blot 分析,大约减少了5-10%的正常水平(来源:J:85344)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
4
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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