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8、9和10号外显子被通过同源重组插入了诺美西林选择标记 cassette。删除区域编码了162到257的氨基酸，已证明对于催化活性是必需的。在纯合突变ES细胞和小鼠的 Western blot 检测中未检测到该蛋白质。(来源：J:85733)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
