一种新霉素选择 cassette 替换了 ex1。来自纯合小鼠脑组织的 Western blot 分析证实,这个等位基因没有产生可检测到的蛋白质。(来源:J:77048)
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A neomycin selection cassette replaced exon 1. Western blot analysis on brain extracts derived from homozygous mice confirmed that no detectable protein was made from this allele. (J:77048)