内源性位点通过插入包含IRES-lacZ和floxed neo的 cassette,其编码区域被干扰。Nat2特异底物去乙酰化缺失及肝脏匀浆的Western blot分析,表明功能蛋白缺失。lacZ的表达由内源性启动子驱动。(来源:J:84738)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
1
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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