intron 1 的一部分和 exon 2 的前半部分被反向插入了抗氨苄青霉素基因,导致阅读框中断。Northern blot 检测显示未产生 mRNA。(来源:J:85229)
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Part of intron 1 and the first half of exon 2 was replaced with a neomycin resistance gene in inverse orientation. This results in disruption of the reading frame. Northern blot analysis indicated that no mRNA was produced. (J:85229)