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中文
通过体内Cre介导的重组，从Ptchtm1Bjw中去除了包含第3外显子和FRT引导的neo cassette的floxed序列。在突变小鼠中通过RT-PCR分析检测到了剪切后缺失区域的片段转录本。突变转录本编码了前117个氨基酸，接着是24个错义突变，以及一个终止密码子，推测导致蛋白质在第一个跨膜域后约被截短了13个氨基酸。(来源：J:85040)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
