第六外显子被通过同源重组插入了诺姆西林选择标记 cassette,用 Western blot 对来自纯合突变的 CD4+ T 细胞检测时未检测到该蛋白。(来源:J:85148)
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Exon 6 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of CD4+ T cells obtained from homozygous mutations. (J:85148)