这项反转是通过Cre-loxP重组酶工程实现的,22厘米(23.0兆碱基)的反转区间被D4Mit281和D4Mit51标记,位于人类染色体1的p臂上。靶向载体中包含了Agouti和酪氨酸酶标记。(来源:J:84714)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
倒位
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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