在通过体内Cre介导的重组去除Mdm2tm1Mep中携带的floxed puromycin选择子后,7号、8号和9号外显子的单个LoxP位点仍保持。 Western blot结果显示,LoxP位点并未干扰蛋白表达。(来源:J:81065)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
插入
--
1
5
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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