Slc4a1^l11Jus51

This phenotypic mutant was identified in an ENU mutagenesis screen at the Baylor College of Medicine. It failed to complement the existing mutation Slc4a1tm1Llp. The mutation was identified as an A-to-T transversion resulting in a missense mutation in the codon corresponding to amino acid 541. This conserved glutamic acid within the fifth transmembrane domain is changed to a valine in the encoded protein. (J:85113)