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这个序列编码的人类MLLT3 3'端从1634号核苷酸延伸到终止密码子，替换了小鼠Kmt2a exon 8的3'部分。导向载体中还包括了一个下游的neo cassette用于选择。生成的融合产物据信模拟了在伴有T(9;11)(p22;q23)关联急性髓系白血病(AML)的患者中产生的KMT2A(MLL)/MLLT3蛋白。(来源：J:75959)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
