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中文
内源性位点被编码绿色荧光蛋白(GFP)的序列插入所打断，这取代了编码exon 2的前390bp。删除区域编码了与内源性配体Cx3cl1相互作用至关重要的蛋白质氨基端部分。针对选择的载体中包含的floxed neo基因在传代前被剔除了，使得GFP序列下游仅留下一个loxP位点。RT-PCR和流式细胞术结果显示，野生型小鼠中无内源性蛋白表达，而纯合突变鼠则表现出GFP表达。(来源：J:84544)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
