首个编码外显子通过体内Cre介导的重组被剪切。同源纯合突变小鼠的 Western blot 分析证实了正常蛋白的缺失。(来源:J:84300)
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The first coding exon was excised via in vivo cre mediated recombination. Western blot analysis of homozygous mutant mice confirmed the absence of normal protein. (J:84300)