一个诺他霉素选择座替换了4、5和6号染色体的序列,导致丧失了VI和VII、VIII号的激酶亚基。E11.5胚胎的蛋白质提取物经 Western blot 分析显示,全长度和部分缺失的蛋白均不存在。(来源:J:84382)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
STOCK 129/Sv and C57BL/6J and SJL
Targeted
插入,基因内删除
--
1
5
34

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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