将一个1.8kb的PGK-neomycin cassette以"顺式"方式插入了包含TM1和TM2区域的第12外显子中。在同卵双胞胎的整个大脑匀浆中未检测到可识别的mRNA,且通过免疫学方法证实了基因产物的缺失。(来源:J:84336)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
2
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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