Exon 2, the initial coding section, was surrounded by a loxP-frt-neo-frt sequence in intron 1 and a single loxP site in intron 2. Mice with this particular genetic variation were mated with cre transgenic mice to produce the strain Foxo3tm1.1Rdp (source: J:84269).
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Exon 2, which is the first coding exon, was flanked by a loxP-frt-neo-frt cassette in intron 1 and single loxP site in intron 2. Mice carrying this allele were bred with cre transgenic mice to generate Foxo3tm1.1Rdp. (J:84269)