在编码ankyrin重复区的第4外显子中插入了耐氨苄青霉素基因。通过RT-PCR和Northern blot在纯合动物的三叉神经根和背根神经节的转录本检测不到。背根神经节的免疫组化染色证实了基因敲除的成功。(来源:J:84093)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入
--
1
22
88

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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