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中文
在exon 1的3个主要部分以及内含子1的一小段序列被替换为编码牛tau蛋白N端的DNA序列，该序列与lacZ基因相连。针对这一目标基因的mRNA和蛋白质在纯合子小鼠的脑中检测不到，而在杂合子中有所减少。(来源：J:84116)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
