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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Plcd1
tm1Tta
Alias:
PLCdelta-deficient
PLCgamma1
-
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基础信息
表型特征
文献报道
编码X和Y催化区域的序列被替换了 neo抗药性基因座。对纯合子睾丸蛋白的 Western blot 检测显示没有基因产物。使用针对N端60个氨基酸的抗体确认了没有产物存在。(来源:J:83948)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2667234
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
2
13
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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