在WEC9.6细胞中,基因的编码区域被替换为一个PGK-puromycin抗性 cassette,这个细胞中Hist1h1c和Hist1he基因已经过修改。通过E7.5胚胎的DNA进行PCR检测,确认了同源重组的正确性。E10.5胚胎提取物的反相高效液相色谱结果显示没有基因产物存在。(来源:J:83954)
Basic Information
STOCK 129/Sv and C57BL/6J and SJL
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count