使用WC1.16细胞,该基因的整个编码区域被替换为PGK-neo cassette,这些细胞已经携带了Hist1h1c的修改。仅使用了含有这两种基因表观修饰的ES细胞克隆来生成转基因小鼠。基因产物的缺失通过反相高效液相色谱进行了验证。(来源:J:83954)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
STOCK 129/Sv and C57BL/6J and SJL
Targeted
插入,基因内删除
--
1
2
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部