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中文
这个基因通过同源重组的方式，用诺美霉素抗性基因 cassette 替换了第3外显子，导致其失活。通过对异源纯合突变动物的甲状腺组织进行免疫组化检测，确实证实了基因表达的缺失（来源：J:76407）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
