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中文
在exon 11引入了一个点突变，移除了558位的缬氨酸，并通过同源重组在intron 9插入了一个floxed neo cassette。这个点突变模拟了人类体细胞胃肠道间质瘤中发现的559位缬氨酸缺失。随后，通过与cre删除型小鼠TgN(EIIa-cre)C5379Lmgd杂交，去除了这个floxed neo cassette。V558位缺失的完整性通过DNA序列分析得到了确认。(来源：J:83616)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
