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中文
这个转基因包含了小鼠Plp启动子区域（包括exons 1和2）和一个cre-ESR1元件。人类ESR1序列在配体结合域被修改为G400V、M543A和L540A，以使其能被4-羟基他莫昔芬（OHT）和ICI 182,780激活。15kb的鼠Plp启动子序列驱动在 oligodendrocytes 和 Schwann 细胞中的转录。（来源：J:83361）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
