在Pofut1tm2Pst中,通过同源重组和体外Cre介导的剪切后,保留了一个loxP位点,替代了exon 2。据推测,exon 2的缺失可能导致exon 3的终止密码突变。在同卵双胞胎胚胎中,通过全基因组印迹检测未检测到转录本。(来源:J:83299)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
STOCK 129/Sv and C57BL/6J and SJL
Targeted
基因内删除
--
1
2
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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